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Hichem's R&D:
Research Terms:
Senior Researchers : 12
Chemical-engineers over 10-year's experience in scale-up: 8
Analysis Equipments:
Supported by Shanghai Institute of Pharmaceutical Indsutry ,
we have complete normal equipment for our research like
IR, UV, NMR, HNMR MS, Polarimeter
HPLC, HPLC-MS, Preparative HPLC
CGC, GC-MS
TLC Scanner
Professional Advantages in pharmaceuticals:
| 1. |
Broad background in drug design of novel enzyme inhibitors and receptor antagonists related to research areas of b-Lactam antibiotics, cardiovascular, AIDS-virus and central nervous systems as new drug candidates. |
| 2. |
The pre-clinic trials of anti-cerebral ischemic agents, novel non-opium analgesics and new type of anti-depressant in progress. |
| 3. |
Expertise in synthesis of chiral intermediates by using chemical and enzymic resolution or asymmetric synthesis techniques. |
| 4. |
Extensive experiences in synthesis of Isoflavone compounds, Boron derivatives and Porphyrin Analogues. |
| 5. |
Liquid-phase synthesis of the polypeptides in scale-up. |
| 6. |
Pilot-scale production and process optimization of key intermediates. |
Experience for following projects:
- HIV enzyme depressor for new drug of anti-aids
- antisense nucleic acid for new drugs of anti-molecule gene disease
- isoflavone compounds applying in anti-cancer and nerve center system
- anti-cerebral-ischemia apoplexy
- anti-aged-imbecile, anti-melancholia and nerve center anodyne
- New drumnone-aspirin anodyne
- anti-angina and hypertension like Diltiazem HCl
- New drug AG for anti-haematoblast-manifold
- Grade III new drug FV for anti terminal galactophore cancer
- Grade III new drug DT for anti-retch from chemical-cure
- SPP for anti-Parkinsons¡¯s disease
- Grade III new drug for anti gynecological infection
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